Which of the following is an example of a thiazide-like diuretic?

Metolazone is classified as a thiazide-like diuretic, which differentiates it from traditional thiazide diuretics. Thiazide-like diuretics are noted for their ability to effectively reduce blood pressure and promote diuresis by acting on the distal convoluted tubule of the kidney. Metolazone, in particular, is often used in patients with heart failure, especially those with edema that does not adequately respond to thiazide diuretics alone.

Hydrochlorothiazide is indeed a thiazide diuretic, and while it is effective, it is not considered a thiazide-like diuretic. Furosemide, on the other hand, is a loop diuretic, which works on the loop of Henle and is often used in more severe cases of fluid overload. Ramilis (likely a misspelling of Ramipril) is not a diuretic; it is an ACE inhibitor used primarily for managing hypertension and heart failure.

Understanding the classifications of diuretics helps in selecting appropriate medications for patients with heart failure, with thiazide-like diuretics offering benefits in cases where thiazides are insufficient.