Which medication is indicated for patients with HFrEF who have a resting heart rate of 70 bpm or higher?

Ivabradine is specifically indicated for patients with heart failure with reduced ejection fraction (HFrEF) who have a resting heart rate of 70 beats per minute (bpm) or higher. The primary function of Ivabradine is to reduce heart rate by selectively inhibiting the sinoatrial node's "funny" current (I_f), which can lead to improved heart efficiency and reduced symptoms of heart failure.

For patients with HFrEF, particularly those who are already on guideline-directed medical therapy, maintaining a lower heart rate can help reduce myocardial oxygen demand and improve outcomes. The use of Ivabradine is particularly beneficial for patients who cannot tolerate beta-blockers or for whom beta-blockers do not sufficiently control the heart rate.

The other medications mentioned have different primary indications: furosemide, bumetanide, and torsemide are loop diuretics primarily used to manage fluid overload in heart failure but do not have the targeted effect on heart rate that Ivabradine provides. Thus, the appropriateness of Ivabradine in patients with HFrEF and a resting heart rate of 70 bpm or higher makes it the correct choice in this scenario.