What is the typical subcutaneous prophylaxis dosing for heparin in Atrial fibrillation?

The recommended dosing for heparin when used for prophylaxis in patients with atrial fibrillation, particularly those at higher risk for thromboembolic events or those who may be immobile, typically involves administering 5000 units subcutaneously three times a day. This regimen is designed to maintain a sufficient anticoagulant level to prevent the formation of clots while minimizing the risk of bleeding.

In patients with atrial fibrillation, the risk of stroke and clot formation is elevated, especially in certain populations. The three times daily dosing provides a more consistent anticoagulant effect compared to less frequent dosing, ensuring that patients remain adequately protected from thromboembolism during times of increased risk.

Other dosing options may not provide the necessary prophylactic coverage as effectively or may lead to inadequate anticoagulation, which can increase the risk of complications associated with atrial fibrillation. Therefore, the dosage of 5000 units three times a day is aligned with established clinical guidelines for thromboprophylaxis management in such patients.