What is the starting dose for hydralazine in the chronic treatment of heart failure?

The starting dose of hydralazine in the chronic treatment of heart failure is typically 12.5 mg orally three times daily. This dosage is important because it allows for a gradual introduction of the medication to the patient's regimen. Starting with a lower dose helps minimize the risk of side effects and allows the healthcare provider to assess the patient's tolerance to the medication.

Hydralazine is a vasodilator, and its primary role in treating heart failure is to decrease afterload, which can help improve cardiac output and relieve symptoms of congestion. By initiating treatment with a low dose, clinicians can then adjust the dosage based on the patient's response and any potential adverse effects, following the principle of starting low and titrating up as necessary. Maintaining close monitoring during this initial phase is essential to ensure the safety and efficacy of the treatment.