What is the preferred non-invasive test to diagnose cardiac amyloidosis?

The preferred non-invasive test to diagnose cardiac amyloidosis is echo with cardiac MRI. This approach is particularly effective because echocardiography can assess cardiac structure and function, revealing characteristic changes associated with amyloidosis, such as diastolic dysfunction and left ventricular thickening. When combined with cardiac MRI, which offers more detailed imaging of the myocardium, it enhances the ability to confirm the presence of amyloid deposits through late gadolinium enhancement.

This combination allows for a comprehensive evaluation of cardiac anatomy and function while providing specific characteristics that help differentiate cardiac amyloidosis from other forms of heart disease. It's an important strategy in clinical practice, as it minimizes the need for more invasive procedures while providing valuable diagnostic information.