What is a primary reason for fatigue in heart failure patients?

Decreased cardiac reserve is a primary reason for fatigue in heart failure patients because, in heart failure, the heart's ability to pump blood effectively is compromised. This leads to inadequate blood flow and oxygen delivery to the body’s organs and tissues during periods of increased physical demand or stress. As a result, patients experience fatigue because their body cannot meet the energy demands due to the inefficient function of the heart.

When the heart struggles to maintain an adequate cardiac output, it can cause lethargy and exhaustion, especially after exertion. Muscle cells and other tissues do not receive enough oxygen and nutrients, making it difficult for patients to engage in normal activities, further exacerbating their sense of fatigue. Additionally, the overall increase in peripheral vascular resistance in heart failure patients makes it harder for their cardiovascular system to respond effectively to increased activity, leading to a feeling of tiredness.