What does the term "destination therapy" refer to in heart failure treatment?

The term "destination therapy" refers to a long-term support strategy for patients with advanced heart failure who are not candidates for heart transplantation. It often involves the use of durable mechanical circulatory support devices, such as ventricular assist devices (VADs), which are intended to improve the quality of life and extend survival for patients with severe heart dysfunction. This approach is distinct from a short-term treatment option, which may aim for immediate stabilization rather than ongoing management. It is also not designed for complete heart recovery as that would imply a more curative approach, which does not align with the objective of providing lifelong support to those with irreversible heart failure. Furthermore, while destination therapy may encompass elements of palliative care by focusing on quality of life, it is not categorized solely as a palliative measure. Instead, it signifies a commitment to sustained management and support.